In order to keep email from taking over my vacation I have created a custom defer folder on SaneBox called @SaneVacation. It is similar to how I use SaneBox to defer emails during the year, except that the defer date is set to my first working day rather than to, say, next Tuesday. I have also created a MailActOn shortcut ^V to move emails that can wait to the @SaneVacation mailbox. They will automatically re-appear in the Inbox after the end of vacation.
All that is left to do is to set an auto-response. The shorter the better. For example, “I am out of office with limited email access until xxx”. As for Macademic, I hope to keep it going. Have a nice summer!